Reigning Kenya Handball Federation women champions Nairobi Water will be battling Ulinzi Sharks as the league continues at Nyayo stadium.
The water providers’ win will be an opportunity to go top of the table.
Second placed National Cereals and Produce Board (NCPB) will face off with third-placed Ulinzi.
Elsewhere, Cereals play Boomerang, Gunners meet Kenyatta University, Vickers tackle Generation as Rangers confront Tigers.
Sunday fixtures will see Boomerang fight with Tigers, Rangers take on Technical University of Kenya (TUK) and Vickers play Kenyatta University.